There are loads to choose from see the list below, I'm opting for Braniac or Doomsday.

Lex Luthor: Superman's most well-known enemy. Pre-Crisis, Luthor was a rogue scientific genius with a personal vendetta against Superman, using his scientific prowess to destroy the Man of Steel by any means possible. Post-Crisis, Luthor is portrayed as a powerful but corrupt CEO of a conglomerate called LexCorp, but still has the same hatred of Superman. Recently, his public downfall has resulted in him returning more to his pre-Crisis persona. Actors portraying Lex have included Gene Hackman, John Shea, Clancy Brown (voice), Michael Rosenbaum and Kevin Spacey.

Darkseid: A cruel and merciless alien who rules the planet Apokolips and only deals with Superman when it benefits his own agenda. Not originally created as a Superman villain, but by Jack Kirby for his New Gods series. Actors portraying Darkseid have included Frank Welker and Michael Ironside.

Bizarro: An imperfect duplicate of Superman. Pre-Crisis, Bizarro was created by an imperfect duplicator ray, and later reappeared as a warped version of Superman from the twisted "Bizarro-World"; post-Crisis, he originally was a failed experiment of Lex Luthor's. More recently, a newer version similar to the pre-Crisis version was reintroduced.

Metallo: A cyborg criminal who prefers using kryptonite as his power source, which makes him a deadly threat to Superman.

Mongul: An alien tyrant, notable as one of the few villains to be as strong as Superman. Mongul aided the Cyborg Superman in his attempt to turn Earth into a new Warworld.

Mr. Mxyzptlk: A being from the fifth dimension with magical powers who delights in tormenting Superman and traditionally could only be made to return to his native dimension by being made to say or spell his own name backwards.

Brainiac: An alien scientist from the planet Colu, intent on conquring Earth; pre-Crisis, Brainiac was portrayed as being an android. Post-Crisis, he was portrayed as a circus mentalist named Milton Fine who was possessed by a Coluan intelligence. During The Doomsday Wars storyline, however, Fine's body was destroyed and Brainiac once more inhabited a robotic body.

Phantom Zone criminals: Pre-Crisis, these were Kryptonian criminals imprisoned in a dimension called the "Phantom Zone", in which they only existed in a ghostlike form; this allowed them to survive the destruction of Krypton. Various such criminals would sometimes escape and attack Superman.
 
General Zod: Pre-Crisis, Zod was one of the main Phantom Zone criminals that fought with Superman. Post-Crisis, Zod was first depicted as a Phantom Zone criminal that Superman encountered in an alternate dimension; eventually, this Zod was killed by Superman with kryptonite. A second version of Zod was later introduced as a product of Soviet genetic engineering, surgically altered to mimic Superman. A third version, wearing black armor, was introduced as a Phantom Zone criminal.

Parasite: A janitor (Maxwell Jensen pre-Crisis; Rudy Jones post-Crisis) who had been mutated into a super-powered man who could absorb the powers, strength, and memories of any organic being, and wanted Superman's power for himself.

The Prankster: A villain who uses various practical jokes as a motif in his crimes. His real name is Oswald Loomis.

Terra-Man: Pre-Crisis, a cowboy-dressed villain who uses various high-tech weapons disguised as those of the American Old West.

Intergang: A nationwide organized crime syndicate armed with weapons supplied in part by Darkseid.

Doomsday: A mindless, impossibly powerful, raging monster that killed Superman during the Death of Superman storyline. During the Last Laugh storyline, a "jokerized" Doomsday that had been reengineered with changes from Superman's DNA attained intelligence; Darkseid and Luthor apparently had a deal to make clones of Doomsday. A version of Doomsday seen recently attained more than just the ability to talk, but the ability to reason and experience emotion, which ultimately turned him from an evil monster to a hero that saved Superman in the present and in an alternate future.

Imperiex: An all-powerful force of nature whose purpose is destroying galaxies. Eventually, Superman, Steel, and Darkseid stopped Imperiex by using Doomsday as an ally, along with a powerful weapon called the Entropy Aegis.

Toyman: An insane criminal who uses special equipment and weapons based on toys.
The Cyborg Superman: A reanimated astronaut cyborg who briefly impersonated Superman after his death, and also destroyed Green Lantern Hal Jordan's home of Coast City.
Effron the Sorcerer: A sorcerer who came from the magic kingdom of Veliathan and controlled a faceless puppet army.

Gog: A human from the future who masters time travel, and hates Superman for allowing his parents to die.

Preus : Formerly a law enforcement officer from the bottle city of Kandor, he escaped the city and hunts Superman.

Ultraman: An evil counterpart of Superman from an alternate Earth, Ultraman possesses powers similar to Superman's. Post-Crisis, Ultraman's power source is through exposure to Anti-Kryptonite instead of his Earth's yellow sun. Ultraman is a member of the Crime Syndicate of America, a villainous version of the Justice League indigenous to his universe.
The Kryptonite Man: Pre-Crisis, a criminal with space-acquired kryptonite radiation powers; post-crisis, similar but originated as a clone of Superman or in an experiment with kryptonite.
Livewire: A woman who can control electricity. She first appeared in the animated series, and has recently been added into the comics.

"Conduit": A good friend of Clark Kent's while growing up, was exposed to Kryptonite Radiation as a baby and so became a living Kryptonite battery. Obsessed with coming in second to Clark and killing both Clark and Superman; has learned they are one and the same. Deceased.

Deathrap: Carl Draper, a master trapmaker, was hired to build a trap to contain The Parasite. However, when his daughter challenges him to trap Superman, he wholeheartedly accepted it. He would appear to Superman as a hologram and challenge him to escape the traps he created.

Neutron (DC Comics): Nathaniel Tryon was a petty thug and a member of the TNT trio before an accident transformed him into living nuclear energy.

it looks like there may not be a superman sequel but they may do a JLA film instead. would ever that is just a rumor

Could be ok, the first film was decent apart from the appaling Kate Bosworth who had absoloutley no on screen chemistry with Brandon,so i hope they will change the actress this time around for Lois Lane.

There are some rumours going around it could be Scarlett J. I hope thats not true. It needs to be Liv Tyler.

Latest news on the stop start Superman sequel From Bryan Singer...

Earlier today, IESB reported that there was a strong rumour that Bryan Singer was working on a sequel to Superman Returns and that Transformers' Roberto Orci and Alex Kurtzman would be writing the script. Well, we've spoken to Singer and, though we have no news on whether the Orci/Kurtzman story is true, he's confirmed that work's under way on the film that some said would never happen because the first was perceived as a flop.

"That movie made $400 million!" Singer says incredulously. "I dont know what constitutes under-performing these days...Look, I can understand, I suppose, what some people mean. Perhaps some people went in with the expectation of it being like an X-Men film, and Superman is a tougher character than that. Especially bringing him back. It really goes back to the fact that you can only please some of the people some of the time. But, yes, Im just getting back with writers after the strike. Were just in the development phase. Im starting to develop a sequel...with the intention of directing it."

Singer knows that there was some negative reaction to the fact that the first film focused more on story at the expense of action and is looking to redress that next time.

The first one was a romantic film and a nostalgic film, he says. Ill be the first person to own up to that without making any apologies for it. I knew it was going to be that from the outset. And now that the characters are established, theres really an opportunity to up the threat levels...Clearly therell be a body count [laughs]. From frame one, it will be unrelenting terror! All those teenage girls who found the movie and mooned over James Marsden or Brandon? Well, Im going to wake them up! He may be joking about the unrelenting terror.

We have to say, we actually enjoyed a huge amount about Superman Returns. Brandon Routh made a terrific Superman and Clark Kent and Singer clearly cared about the characters. It was light on action, so it would be great to see a sequel in which we get to actually experience what Supes can really do.

There could be problems with getting this made now.....

LOS ANGELES Time Warner is no longer the sole proprietor of Superman.

A federal judge here on Wednesday ruled that the heirs of Jerome Siegel who 70 years ago sold the rights to the action hero he created with Joseph Shuster to Detective Comics for $130 were entitled to claim a share of the United States copyright to the character. The ruling left intact Time Warners international rights to the character, which it has long owned through its DC Comics unit.

And it reserved for trial questions over how much the company may owe the Siegel heirs for use of the character since 1999, when their ownership is deemed to have been restored. Also to be resolved is whether the heirs are entitled to payments directly from Time Warners film unit, Warner Brothers, which took in $200 million at the domestic box office with Superman Returns in 2006, or only from the DC units Superman profits.

Still, the ruling threatened to complicate Warners plans to make more films featuring Superman, including another sequel and a planned movie based on the DC Comics Justice League of America, in which he joins Batman, Wonder Woman and other superheroes to battle evildoers.

If the ruling survives a Time Warner legal challenge, it may also open the door to a similar reversion of rights to the estate of Mr. Shuster in 2013. That would give heirs of the two creators control over use of their lucrative character until at least 2033 and perhaps longer, if Congress once again extends copyright terms according to Marc Toberoff, a lawyer who represents the Siegels and the Shuster estate.

It would be very powerful, said Mr. Toberoff, speaking by telephone on Friday. After 2013, Time Warner couldnt exploit any new Superman-derived works without a license from the Siegels and Shusters.

Time Warner lawyers declined to discuss the decision, a spokesman said. A similar ruling in 2006 allowed the Siegels to recapture their rights in the Superboy character, without determining whether Superboy was, in fact, the basis for Warner Brotherss Smallville television series. The decision was later challenged in a case that has yet to be resolved, said Mr. Toberoff, who represented the family in that action.

This weeks decision by Stephen G. Larson, a judge in the Federal District Court for the Central District of California, provided long-sought vindication to the wife and daughter of Mr. Siegel, who had bemoaned until his death in 1996 having parted so cheaply with rights to the lucrative hero.

We were just stubborn, Joanne Siegel, Mr. Siegels widow, said in a joint interview with her daughter, Laura Siegel Larson. It was a dream of Jerrys, and we just took up the task.

The ruling specifically upheld the Siegels copyright in the Superman material published in Detective Comics Action Comics Vol. 1. The extent to which later iterations of the character are derived from that original was not determined by the judge.

In an unusually detailed narrative, the judges 72-page order described how Mr. Siegel and Mr. Shuster, as teenagers at Glenville High School in Cleveland, became friends and collaborators on their school newspaper in 1932. They worked together on a short story, The Reign of the Superman, in which their famous character first appeared not as hero, but villain.

By 1937, the pair were offering publishers comic strips in which the classic Superman elements cape, logo and Clark Kent alter-ego were already set. When Detective Comics bought 13 pages of work for its new Action Comics series the next year, the company sent Mr. Siegel a check for $130, and received in return a release from both creators granting the company rights to Superman to have and hold forever, the order noted.

In the late 1940s, a referee in a New York court upheld Detective Comics copyright, prompting Mr. Siegel and Mr. Shuster to drop their claim in exchange for $94,000. More than 30 years later, DC Comics (the successor to Detective Comics) gave the creators each a $20,000-per-year annuity that was later increased to $30,000. In 1997, however, Mrs. Siegel and her daughter served copyright termination notices under provisions of a 1976 law that permits heirs, under certain circumstances, to recover rights to creations.

Mr. Toberoff, their lawyer, has been something of a gadfly to Warner in the past. In the late 1990s, for example, he represented Gilbert Ralston, a television writer, in a legal battle over his rights in the CBS television series The Wild Wild West, which was the basis for a 1999 Warner Brothers film that starred Will Smith. The case, said Mr. Toberoff, was settled.

Compensation to the Siegels would be limited to any work created after their 1999 termination date. Income from the 1978 Superman film, or the three sequels that followed in the 1980s, are not at issue. But a Superman Returns sequel being planned with the filmmaker Bryan Singer (who has also directed The Usual Suspects and X-Men) might require payments to the Siegels, should they prevail in a demand that the studios income, not just that of the comics unit, be subject to a court-ordered accounting.

Mrs. Siegel and Ms. Larson said it was too soon to make future plans for the Superman character. But they were inclined to relish this moment.

I have lived in the shadow of this my whole life, Ms. Larson said. I am so happy now, I just cant explain it.

This article has been revised to reflect the following correction:

Correction: April 1, 2008
A picture caption with an article on Saturday about a legal victory for the heirs of Jerry Siegel, a creator of the Superman action character, misstated the given name of his co-creator. He was Joe Shuster, not Max. The article also misspelled Mr. Siegels family name as Seigel in one reference.


Although if it does they are considering goin in this direction...

Legendary's roster of upcoming films includes a wide variety of properties, including Watchmen (from the renowned graphic novel), Akira (a remake of the popular Japanese anime film), a Superman sequel (in
Which Tull hopes to invoke more of the image of "an angry god"), Clash of the Titans, Where the Wild Things Are and a film of Paradise Lost (Tull is particularly interested in the "[story] arc of Lucifer").